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rEVO Biologics

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Atryn	Antithrombin alfa	2009-02-06		Antithrombin iii deficiency

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

Antithrombin alfa

cardiopulmonary bypass

,

postoperative hemorrhage

,

,

,

venous thrombosis

,

antithrombin iii deficiency

,

ocular hypertension

,

,

,

corneal wavefront aberration

,

,

cardiopulmonary bypass

,

postoperative hemorrhage

migraine disorders

,

precursor cell lymphoblastic leukemia-lymphoma

,

hepatic insufficiency

,

,

,

transplantation

,

dermatomyositis

,

,

central nervous system neoplasms

,

germ cell and embryonal neoplasms

,

liver neoplasms

,

nervous system neoplasms

,

dna repair-deficiency disorders

,

hereditary congenital and neonatal diseases and abnormalities

,

,

hypoplastic anemia congenital

,

hemic and lymphatic diseases

,

adenosquamous carcinoma

,

thoracic neoplasms

,

esophageal neoplasms

,

,

squamous cell carcinoma of head and neck

,

,

,

kidney neoplasms

,

bites and stings

,

pancreatic neoplasms

,

ovarian neoplasms

,

castration-resistant prostatic neoplasms

,

myeloid leukemia acute

,

renal cell carcinoma

,

graft vs host disease

,

carcinoid tumor

,

type 1 diabetes mellitus

,

invasive hydatidiform mole

,

myeloid leukemia

,

,

,

acquired immunodeficiency syndrome

,

,

,

b-cell lymphoma

,

smoldering multiple myeloma

,

gastrointestinal neoplasms

,

urinary bladder neoplasms

,

,

,

uterine neoplasms

,

female genital neoplasms

,

hematopoietic stem cell transplantation

,

thyroid neoplasms

,

endocrine gland neoplasms

,

parathyroid neoplasms

,

,

giant cell tumors

,

,

second primary neoplasms

,

chronic urticaria

,

parkinson disease

,

aplastic anemia

,

mucocutaneous lymph node syndrome

,

fallopian tube neoplasms

,

,

urologic neoplasms

,

transitional cell carcinoma

,

ureteral neoplasms

,

serotonin syndrome

,

malignant pleural effusion

,

circulating neoplastic cells

,

myelomonocytic leukemia juvenile

,

bcr-abl positive chronic myelogenous leukemia

,

,

replacement arthroplasty hip

,

,

aneurysmal bone cysts

,

giant cell granuloma

,

,

chondroblastoma

,

deglutition disorders

,

,

brain neoplasms

,

kidney transplantation

,

graft rejection

,

psychology rejection

,

triple negative breast neoplasms

,

,

,

breast neoplasms

,

non-small-cell lung carcinoma

,

neoplasm metastasis

,

multiple myeloma

,

rectal neoplasms

,

,

colonic neoplasms

,

head and neck neoplasms

,

plasma cell neoplasms

,

,

non-hodgkin lymphoma

,

prostatic neoplasms

,

hematologic neoplasms

,

myelodysplastic syndromes

,

,

,

stomach neoplasms

,

,

,

,

,

squamous cell neoplasms

,

,

,

,

,

squamous cell carcinoma

,

,

hodgkin disease

,

follicular lymphoma

,

large b-cell lymphoma diffuse

,

juvenile arthritis

,

thrombocytopenic purpura idiopathic

,

thrombocytopenia

,

thrombocytopenic purpura

,

,

mucinous adenocarcinoma

,

,

,

small cell lung carcinoma

,

b-cell chronic lymphocytic leukemia

,

hematologic diseases

,

,

spinal cord compression

,

,

hypercholesterolemia

,

inflammatory breast neoplasms

,

,

metabolic diseases

,

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

ankylosing spondylitis

,

spondylarthropathies

,

spondylarthritis

,

,

febrile neutropenia

,

cardiovascular diseases

,

ventricular dysfunction

,

sezary syndrome

,

precancerous conditions

,

lymphoproliferative disorders

,

prolymphocytic leukemia

,

mantle-cell lymphoma

,

waldenstrom macroglobulinemia

,

large-cell lymphoma anaplastic

,

immunoblastic lymphadenopathy

,

mycosis fungoides

,

t-cell lymphoma cutaneous

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

immunoglobulin light-chain amyloidosis

,

large granular lymphocytic leukemia

,

large-cell lymphoma immunoblastic

,

monoclonal gammopathy of undetermined significance

,

osteogenesis imperfecta

,

musculoskeletal diseases

,

blood protein disorders

,

bone marrow diseases

,

paraproteinemias

,

neoplastic processes

,

multiple endocrine neoplasia type 1

,

,

personal satisfaction

,

,

hyperlipoproteinemia type ii

,

ductal carcinoma breast

,

hemostatic disorders

,

critical illness

,

,

,

laryngeal diseases

,

,

esophageal squamous cell carcinoma

,

phenylketonurias

,

feeding and eating disorders

,

anorexia nervosa

,

,

,

,

colorectal neoplasms

,

,

,

chronic renal insufficiency

,

rheumatoid arthritis

,

kidney diseases

,

metabolic bone diseases

,

postmenopausal osteoporosis

,

,

,

healthy volunteers/patients

,

psoriatic arthritis

,

chronic kidney failure

,

renal insufficiency

,

giant cell tumor of bone

,

,

,

,

,

erythrocyte transfusion

,

primary hyperparathyroidism

,

,

,

,

autoimmune diseases

,

,

aids-related complex

,

cardiomyopathies

,

,

hyperlipidemias

,

diabetes mellitus

,

insulin resistance

,

metabolic syndrome

,

microvascular angina

,

atherosclerosis

,

hidradenitis suppurativa

healthy volunteers/patients

,

,

,

,

,

postoperative pain

,

chronic kidney failure

,

kidney diseases

,

delayed graft function

,

,

gastroenteritis

,

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