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Trade Name
Drug Name
Approved
Patent Expires
Indication
Atryn
Antithrombin alfa
2009-02-06
Antithrombin iii deficiency
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Antithrombin alfa
congenital heart defects
,
postoperative hemorrhage
,
healthy volunteers/patients
,
renal dialysis
,
covid-19
,
sepsis
,
liver cirrhosis
,
syndrome
,
liver failure
,
hepatic insufficiency
,
venous thromboembolism
,
thromboembolism
,
cardiac surgical procedures
,
reperfusion injury
,
coronary artery bypass
,
respiratory distress syndrome
,
severe acute respiratory syndrome
,
acute lung injury
,
newborn respiratory distress syndrome
,
hepatic veno-occlusive disease
,
end stage liver disease
,
fibrosis
,
acute-on-chronic liver failure
,
wounds and injuries
,
blood coagulation disorders
,
hemostatic disorders
,
venous thrombosis
,
cardiopulmonary bypass
,
disseminated intravascular coagulation
,
extracorporeal membrane oxygenation
,
menopause
,
coronary artery disease
,
percutaneous coronary intervention
,
dual anti-platelet therapy
,
antithrombin iii deficiency
,
thrombosis
,
hemophilia a
,
thrombophilia
,
pre-eclampsia
,
myocardial infarction
,
infarction
,
acute coronary syndrome
,
aortic valve stenosis
,
aortic valve insufficiency
,
mitral valve insufficiency
,
mitral valve stenosis
,
toxemia
,
coagulation protein disorders
,
hemorrhage
,
congenital disorders of glycosylation
,
leukemia
,
atrial fibrillation
,
embolic stroke
,
recurrence
,
multiple sclerosis
,
relapsing-remitting multiple sclerosis
,
sclerosis
,
sickle cell anemia
,
hemolysis
,
hemolytic anemia
,
heart failure
,
thrombocytopenia
,
environmental biomarkers
,
postmenopause
,
cicatrix
,
burns
,
factor xiii deficiency
,
migraine disorders
,
acute-phase reaction
,
antiphospholipid syndrome
,
malnutrition
,
fatal outcome
,
cytokine release syndrome
,
septic shock
,
upper extremity deep vein thrombosis
,
nephritis
,
transfusion reaction
,
liver transplantation
,
heart diseases
,
heart septal defects
,
pancreatitis
,
acute kidney injury
,
portal hypertension
,
embolism
,
budd-chiari syndrome
,
chronic renal insufficiency
,
post-acute covid-19 syndrome
,
precursor cell lymphoblastic leukemia-lymphoma
,
lymphoid leukemia
,
hip fractures
Benzocaine
anxiety disorders
,
healthy volunteers/patients
,
huntington disease
,
non-alcoholic fatty liver disease
,
overweight
,
fatty liver
,
hepatitis b
,
syndrome
,
breast neoplasms
,
neoplasms
,
chronic hepatitis b
,
chronic hepatitis
,
parkinson disease
,
eosinophilic esophagitis
,
pruritus
,
biliary liver cirrhosis
,
cholestasis
,
asthma
,
pulmonary hypertension
,
pulmonary arterial hypertension
,
diffuse scleroderma
,
sclerosis
,
myalgia
,
liver diseases
,
short bowel syndrome
,
myocardial infarction
,
drug resistance
,
heat stress disorders
,
mood disorders
,
combat disorders
,
traumatic stress disorders
,
gastrointestinal diseases
,
constipation
,
intestinal diseases
,
knee osteoarthritis
,
pain
,
osteoarthritis
,
musculoskeletal diseases
,
urinary bladder neoplasms
,
transitional cell carcinoma
,
depressive disorder
,
hepatitis
,
depression
,
major depressive disorder
,
hepatitis a
,
arthritis
,
anemia
,
kidney diseases
,
hepatitis c
,
cardiovascular diseases
,
chronic renal insufficiency
,
chronic hepatitis c
,
papillomavirus infections
,
hypertension
,
inflammation
,
pulmonary embolism
,
embolism
,
thromboembolism
,
thrombosis
,
venous thrombosis
,
infections
,
papillomavirus vaccines
,
meningitis
,
meningococcal infections
,
heart failure
,
glucose metabolism disorders
,
metabolic diseases
,
vascular diseases
,
heart diseases
,
metabolic syndrome
,
endocrine system diseases
,
hypertriglyceridemia
,
rheumatoid arthritis
,
atrial fibrillation
,
type 2 diabetes mellitus
,
diabetes mellitus
,
myositis
,
systemic scleroderma
,
juvenile arthritis
,
behcet syndrome
,
dermatomyositis
,
ankylosing spondylitis
,
sjogren's syndrome
,
systemic lupus erythematosus
,
herpes zoster
,
spondylarthritis
,
systemic vasculitis
,
diabetic neuropathies
,
hypercholesterolemia
,
facial pain
,
facial nerve diseases
,
facies
,
wasting syndrome
,
cachexia
,
keratoconjunctivitis sicca
,
dry eye syndromes
Serine
non-small-cell lung carcinoma
,
lung neoplasms
Bevifimod
healthy volunteers/patients
,
uveal neoplasms
,
cutaneous malignant melanoma
,
uveal melanoma
,
huntington disease
,
uveitis
,
urologic neoplasms
,
plasma cell neoplasms
,
chronic hepatitis c
,
mantle-cell lymphoma
,
biliary tract neoplasms
,
esophageal neoplasms
,
transitional cell carcinoma
,
choroidal neovascularization
,
sarcoma
,
acquired immunodeficiency syndrome
,
fibrosis
,
graft vs host disease
,
central nervous system neoplasms
,
unknown primary neoplasms
,
genomic instability
,
lobular carcinoma
,
invasive hydatidiform mole
,
ischemia
,
coronary artery disease
,
myocardial ischemia
,
stroke
,
subarachnoid hemorrhage
,
aneurysm
,
aids-related complex
,
arthritis
,
esophageal squamous cell carcinoma
,
idiopathic pulmonary fibrosis
,
cholangiocarcinoma
,
emphysema
,
pulmonary emphysema
,
margins of excision
,
waldenstrom macroglobulinemia
,
aids-related lymphoma
,
hemolytic-uremic syndrome
,
thrombotic thrombocytopenic purpura
,
syndrome
,
thrombocytopenic purpura
,
purpura
,
azotemia
,
hereditary sensory and autonomic neuropathies
,
b-cell lymphoma marginal zone
,
uterine neoplasms
,
female genital neoplasms
,
sjogren's syndrome
,
nervous system neoplasms
,
burkitt lymphoma
,
precursor b-cell lymphoblastic leukemia-lymphoma
,
sex cord-gonadal stromal tumors
,
erythema multiforme
,
immunoblastic lymphadenopathy
,
obesity
,
overweight
,
lymphoma
,
large b-cell lymphoma diffuse
,
liver neoplasms
,
b-cell lymphoma
,
hepatocellular carcinoma
,
triple negative breast neoplasms
,
renal cell carcinoma
,
follicular lymphoma
,
rectal neoplasms
,
neoplasm metastasis
,
macular degeneration
,
glioblastoma
,
melanoma
,
adenocarcinoma
,
macular edema
,
multiple myeloma
,
carcinoma
,
pancreatic neoplasms
,
recurrence
,
hematologic neoplasms
,
inflammatory breast neoplasms
,
glioma
,
neoplasms by histologic type
,
neoplasms by site
,
brain neoplasms
,
colonic neoplasms
,
uterine cervical neoplasms
,
type 2 diabetes mellitus
,
ulcerative colitis
,
head and neck neoplasms
,
hemophilia a
,
thrombocytopenic purpura idiopathic
,
relapsing-remitting multiple sclerosis
,
nasal polyps
,
lung neoplasms
,
mucinous adenocarcinoma
,
ductal carcinoma breast
,
urinary bladder neoplasms
,
lymphoproliferative disorders
,
ovarian epithelial carcinoma
,
malignant mesothelioma
,
diabetic retinopathy
,
bronchiolitis obliterans syndrome
,
neuroblastoma
,
hemolysis
,
circulating neoplastic cells
,
retinal diseases
,
vision disorders
,
eye diseases
,
bcr-abl positive chronic myelogenous leukemia
,
pemphigus
,
respiratory tract diseases
,
germ cell and embryonal neoplasms
,
small cell lung carcinoma
,
lung diseases
,
respiratory tract neoplasms
,
bronchogenic carcinoma
,
thoracic neoplasms
,
bronchial diseases
,
nerve tissue neoplasms
,
myeloid leukemia acute
,
guillain-barre syndrome
,
patient preference
,
large-cell lymphoma anaplastic
,
anaplastic thyroid carcinoma
,
papillary thyroid cancer
,
laryngeal neoplasms
,
erdheim-chester disease
,
prostatic neoplasms
,
salivary gland neoplasms
,
skin neoplasms
,
gallbladder neoplasms
,
diabetes mellitus
,
anti-neutrophil cytoplasmic antibody-associated vasculitis
,
membranous glomerulonephritis
,
colitis
,
disability evaluation
,
cognition disorders
,
hemolytic anemia autoimmune
,
nephrotic syndrome
,
focal segmental glomerulosclerosis
,
lipoid nephrosis
,
graft rejection
,
retinal neovascularization
,
type 3 von willebrand disease
,
breast neoplasms
,
colorectal neoplasms
,
non-small-cell lung carcinoma
,
neoplasms
,
rheumatoid arthritis
,
non-hodgkin lymphoma
,
b-cell chronic lymphocytic leukemia
,
anemia
,
hiv infections
,
ovarian neoplasms
,
stomach neoplasms
,
leukemia
,
lymphoid leukemia
,
kidney transplantation
,
chronic hepatitis b
,
heart transplantation
,
chronic kidney failure
,
fallopian tube neoplasms
,
liver transplantation
,
kidney diseases
,
chronic renal insufficiency
,
granulomatosis with polyangiitis
,
peritoneal neoplasms
,
pulmonary fibrosis
,
microscopic polyangiitis
,
renal insufficiency
,
asthma
,
transplantation
,
immunosuppression therapy
,
covid-19
,
polyomavirus infections
,
thrombosis
,
food hypersensitivity
,
liver cirrhosis
,
adenocarcinoma of lung
,
hepatitis b
,
hepatitis
,
hepatitis a
,
off-label use
,
retinal vein occlusion
,
cardiotoxicity
,
acute kidney injury
,
hemorrhage
,
endometrial neoplasms
,
uterine hemorrhage
,
postmenopause
,
hematopoietic stem cell transplantation
,
hiv-1
,
spinal muscular atrophy
,
spinal muscular atrophies of childhood
,
alzheimer disease
,
frontotemporal dementia
,
progressive supranuclear palsy
,
pick disease of the brain
,
hodgkin disease
Nadide
healthy volunteers/patients
,
infections
,
acquired immunodeficiency syndrome
,
hepatitis c
,
non-small-cell lung carcinoma
,
neoplasms
,
bacterial infections
,
toxoplasmosis
,
hepatitis b
,
chronic hepatitis b
,
hepatitis
,
hepatitis a
,
ulcer
,
buruli ulcer
,
hiv infections
,
streptococcal infections
,
pneumococcal infections
,
fever
,
meningococcal infections
,
pneumococcal pneumonia
,
premature birth
,
sexually transmitted diseases
,
herpes simplex
,
prostatic hyperplasia
,
hyperplasia
Crystalloid
healthy volunteers/patients
,
osteoarthritis
,
major depressive disorder
,
prostatic hyperplasia
,
skin aging
,
carpal tunnel syndrome
,
premature ejaculation
,
neuralgia
,
hyperalgesia
,
cicatrix
,
torticollis
,
depression
,
systemic lupus erythematosus
,
muscle spasticity
,
stroke
,
urinary incontinence
,
cerebral palsy
,
migraine disorders
,
multiple sclerosis
,
neurogenic urinary bladder
,
overactive urinary bladder
Rfviia
healthy volunteers/patients
,
hemostasis
,
hemorrhagic disorders
,
intracranial hemorrhages
,
thrombasthenia
,
liver cirrhosis
,
coronary disease
,
acute coronary syndrome
,
fever
,
dengue
,
severe dengue
,
viral hemorrhagic fevers
,
hematoma
,
cystitis
,
fibrosis
,
spinal fusion
,
colonic neoplasms
,
pancreatic neoplasms
,
adenocarcinoma
,
neoplasm metastasis
,
stroke
,
cerebral hemorrhage
,
wounds and injuries
,
factor vii deficiency
,
cardiac surgical procedures
,
congenital heart defects
,
heart diseases
,
coronary artery disease
,
myocardial ischemia
,
heart valve diseases
,
burns
,
hemophilia a
,
hemophilia b
,
blood coagulation disorders
,
hemostatic disorders
,
hemorrhage
,
postpartum hemorrhage
,
deficiency diseases
,
thrombocytopenia
,
hematologic diseases
,
cardiopulmonary bypass
,
hemorrhagic shock
,
traumatic brain hemorrhage
,
factor xi deficiency
,
shock
,
type 3 von willebrand disease
,
thromboembolism
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