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Company ReportsrEVO Biologics

rEVO Biologics

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Atryn	Antithrombin alfa	2009-02-06		Antithrombin iii deficiency

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

Antithrombin alfa

congenital heart defects

,

postoperative hemorrhage

,

healthy volunteers/patients

,

,

,

,

liver cirrhosis

,

,

,

hepatic insufficiency

,

venous thromboembolism

,

thromboembolism

,

cardiac surgical procedures

,

reperfusion injury

,

coronary artery bypass

,

respiratory distress syndrome

,

severe acute respiratory syndrome

,

acute lung injury

,

newborn respiratory distress syndrome

,

hepatic veno-occlusive disease

,

end stage liver disease

,

,

acute-on-chronic liver failure

,

wounds and injuries

,

blood coagulation disorders

,

hemostatic disorders

,

venous thrombosis

,

cardiopulmonary bypass

,

disseminated intravascular coagulation

,

extracorporeal membrane oxygenation

,

,

coronary artery disease

,

percutaneous coronary intervention

,

dual anti-platelet therapy

,

antithrombin iii deficiency

,

,

,

,

,

myocardial infarction

,

,

acute coronary syndrome

,

aortic valve stenosis

,

aortic valve insufficiency

,

mitral valve insufficiency

,

mitral valve stenosis

,

,

coagulation protein disorders

,

,

congenital disorders of glycosylation

,

,

atrial fibrillation

,

,

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

,

sickle cell anemia

,

,

hemolytic anemia

,

,

thrombocytopenia

,

environmental biomarkers

,

,

,

,

factor xiii deficiency

,

migraine disorders

,

acute-phase reaction

,

antiphospholipid syndrome

,

,

,

cytokine release syndrome

,

,

upper extremity deep vein thrombosis

,

,

transfusion reaction

,

liver transplantation

,

,

heart septal defects

,

,

acute kidney injury

,

portal hypertension

,

,

budd-chiari syndrome

,

chronic renal insufficiency

,

post-acute covid-19 syndrome

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

,

gastrointestinal hemorrhage

small cell lung carcinoma

,

,

merkel cell carcinoma

,

non-muscle invasive bladder neoplasms

,

burkitt lymphoma

,

pancreatic ductal carcinoma

,

neurofibromatosis 1

,

hereditary sensory and autonomic neuropathies

,

central nervous system neoplasms

,

,

,

,

drug interactions

,

transitional cell carcinoma

,

uterine cervical neoplasms

,

urinary bladder neoplasms

,

thyroid neoplasms

,

brain concussion

,

post-concussion syndrome

,

,

myeloproliferative disorders

,

b-cell chronic lymphocytic leukemia

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

t-cell lymphoma cutaneous

,

,

mycosis fungoides

,

squamous cell neoplasms

,

postoperative pain

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

lyme neuroborreliosis

,

ocular hypertension

,

open-angle glaucoma

,

triple negative breast neoplasms

,

,

multiple myeloma

,

brain neoplasms

,

,

respiratory syncytial viruses

,

,

hepatocellular carcinoma

,

plasma cell neoplasms

,

head and neck neoplasms

,

ovarian epithelial carcinoma

,

ovarian neoplasms

,

,

hodgkin disease

,

endometrial neoplasms

,

liver neoplasms

,

squamous cell carcinoma

,

atopic dermatitis

,

paraproteinemias

,

pancreatic neoplasms

,

,

esophageal neoplasms

,

hematopoietic stem cell transplantation

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

human influenza

,

oligodendroglioma

,

myelodysplastic syndromes

,

,

,

diabetic retinopathy

,

,

,

,

plasma cell leukemia

,

disease progression

,

,

overactive urinary bladder

,

keratoconjunctivitis sicca

,

dry eye syndromes

,

communicable diseases

,

interstitial cystitis

,

meningococcal infections

,

meningococcal meningitis

,

,

serogroup b neisseria meningitidis

,

hematologic diseases

,

immune system diseases

,

blood protein disorders

,

lymphoproliferative disorders

,

vascular diseases

,

neoplasms by histologic type

,

immunoproliferative disorders

,

hemorrhagic disorders

,

,

waldenstrom macroglobulinemia

,

,

myeloid leukemia

,

malignant mesothelioma

,

,

sickle cell anemia

,

,

monocytic leukemia acute

,

irritable bowel syndrome

,

,

small fiber neuropathy

,

myelomonocytic leukemia chronic

,

discoid lupus erythematosus

,

cutaneous lupus erythematosus

,

meningeal neoplasms

,

breast neoplasms

,

colorectal neoplasms

,

non-small-cell lung carcinoma

,

,

myeloid leukemia acute

,

prostatic neoplasms

,

renal cell carcinoma

,

colonic neoplasms

,

squamous cell carcinoma of head and neck

,

coronavirus infections

,

non-hodgkin lymphoma

,

neoplasm metastasis

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

rectal neoplasms

,

psoriatic arthritis

,

follicular lymphoma

,

,

,

,

juvenile arthritis

,

,

borrelia infections

,

rectal diseases

,

,

,

partial epilepsies

,

kidney neoplasms

,

male breast neoplasms

,

respiratory tract infections

,

stomach neoplasms

,

bacterial infections

,

infectious skin diseases

,

wound infection

,

soft tissue infections

,

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

gastrointestinal diseases

,

intestinal neoplasms

,

digestive system diseases

,

colonic diseases

,

intestinal diseases

,

,

chronic renal insufficiency

,

chronic kidney failure

,

,

endocrine system diseases

,

fetal growth retardation

,

growth disorders

,

hematologic neoplasms

,

invasive pulmonary aspergillosis

,

neuroaspergillosis

,

,

,

febrile neutropenia

,

,

,

bronchiolitis obliterans syndrome

,

lymphoid leukemia

,

restless legs syndrome

,

sleep deprivation

,

complex partial epilepsy

,

metabolic syndrome

,

abdominal obesity

,

pneumococcal infections

,

vector borne diseases

,

,

residual neoplasm

,

carpal tunnel syndrome

,

aplastic anemia

,

polyneuropathies

,

,

liver cirrhosis

,

,

,

,

coronaviridae infections

,

neoplasms by site

,

rheumatoid arthritis

,

,

healthy volunteers/patients

,

,

,

,

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

type 2 diabetes mellitus

,

,

,

ankylosing spondylitis

,

pituitary dwarfism

,

,

,

invasive candidiasis

,

diabetes mellitus

,

,

kidney transplantation

,

precursor b-cell lymphoblastic leukemia-lymphoma

,

,

,

respiratory tract diseases

,

,

pharmacokinetics

,

,

postherpetic neuralgia

,

cardiovascular diseases

,

axial spondyloarthritis

,

,

type 1 diabetes mellitus

,

insulin resistance

,

hemostatic disorders

,

diabetic neuropathies

,

anxiety disorders

,

ventilator-associated pneumonia

,

relapsing-remitting multiple sclerosis

,

,

essential tremor

,

atherosclerosis

,

non-radiographic axial spondyloarthritis

,

electrocardiography

,

smoking cessation

,

traumatic brain injuries

,

,

,

pathologic constriction

,

spinal stenosis

,

,

tissue adhesions

,

,

,

obsessive-compulsive disorder

,

rheumatic fever

,

,

,

,

neisseria meningitidis

,

ulcerative colitis

,

inflammatory bowel diseases

,

,

,

metabolic bone diseases

,

healthcare-associated pneumonia

,

drug-related side effects and adverse reactions

,

,

,

hypercholesterolemia

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

,

,

type 3 von willebrand disease

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