rEVO Biologics - PharmaKB

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rEVO Biologics

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Atryn	Antithrombin alfa	2009-02-06		Antithrombin iii deficiency

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

Antithrombin alfa

congenital heart defects

,

,

postoperative hemorrhage

,

healthy volunteers/patients

,

,

,

liver cirrhosis

,

wounds and injuries

,

,

,

,

hepatic insufficiency

,

venous thromboembolism

,

thromboembolism

,

,

,

reperfusion injury

,

coronary artery bypass

,

cerebral infarction

,

,

ischemic stroke

,

respiratory distress syndrome

,

severe acute respiratory syndrome

,

acute lung injury

,

newborn respiratory distress syndrome

,

hepatic veno-occlusive disease

,

,

small cell lung carcinoma

,

,

communicable diseases

,

end stage liver disease

,

acute-on-chronic liver failure

,

blood coagulation disorders

,

hemostatic disorders

,

cardiopulmonary bypass

,

disseminated intravascular coagulation

,

,

extracorporeal membrane oxygenation

,

type 1 diabetes mellitus

,

,

non-hodgkin lymphoma

,

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

antithrombin iii deficiency

,

,

,

venous thrombosis

,

,

myocardial infarction

,

,

cardiac surgical procedures

,

,

acute coronary syndrome

,

aortic valve stenosis

,

aortic valve insufficiency

,

mitral valve insufficiency

,

pathologic constriction

,

mitral valve stenosis

,

,

coagulation protein disorders

,

nutritional requirements

,

congenital disorders of glycosylation

,

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

,

sickle cell anemia

,

,

hemolytic anemia

,

,

thrombocytopenia

,

environmental biomarkers

,

,

,

,

factor xiii deficiency

,

migraine disorders

,

acute-phase reaction

,

antiphospholipid syndrome

,

,

cytokine release syndrome

,

,

upper extremity deep vein thrombosis

,

,

transfusion reaction

,

liver transplantation

,

,

heart septal defects

,

,

acute kidney injury

,

portal hypertension

,

,

budd-chiari syndrome

,

chronic renal insufficiency

,

kidney diseases

,

renal insufficiency

,

post-acute covid-19 syndrome

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

,

multi-infarct dementia

healthy volunteers/patients

,

pharmacokinetics

,

biological availability

,

prostatic neoplasms

,

medical sociology

,

,

,

drug interactions

,

,

,

chronic kidney failure

,

therapeutic equivalency

,

,

non-small-cell lung carcinoma

,

ischemic stroke

,

replacement arthroplasty knee

,

,

,

bariatric surgery

,

transient ischemic attack

,

cerebral infarction

,

venous thrombosis

,

acute coronary syndrome

,

,

surgical blood loss

,

renal insufficiency

,

postoperative hemorrhage

,

,

,

,

rheumatic diseases

,

myocardial infarction

,

kidney diseases

,

esophageal neoplasms

,

,

respiratory distress syndrome

,

coronavirus infections

,

severe acute respiratory syndrome

,

,

aortic valve stenosis

,

heart valve diseases

,

ventricular outflow obstruction

,

rheumatic heart disease

,

transcatheter aortic valve replacement

,

,

percutaneous coronary intervention

,

unstable angina

,

knee osteoarthritis

,

hip osteoarthritis

,

,

,

chronic renal insufficiency

,

,

respiratory insufficiency

,

communicable diseases

,

collagen diseases

,

coronary disease

,

,

thrombophlebitis

,

atrial fibrillation

,

thromboembolism

,

venous thromboembolism

,

,

,

pulmonary embolism

,

,

,

coronary artery disease

,

peripheral arterial disease

,

,

cardiovascular diseases

,

,

atherosclerosis

,

myocardial ischemia

,

respiratory tract diseases

,

embolism and thrombosis

,

,

,

antiphospholipid syndrome

,

,

intermittent claudication

,

,

carotid stenosis

,

peripheral vascular diseases

,

atherosclerotic plaque

,

vascular diseases

,

replacement arthroplasty hip

,

intracranial hemorrhages

,

disease progression

,

,

,

congenital heart defects

,

fontan procedure

gastroesophageal reflux

,

peptic esophagitis

,

,

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